Apparently there's this concept in academia of the "last lecture"—if you could only lecture once more before you died, what would you say?
Oprah's favorite doctor, Mehmet Oz, heard about an engineer type named Randy Pausch who's dying of pancreatic cancer, and Oprah had Pausch on her show to reprise his "last lecture." The video is here, and it's well worth the 11 minutes it takes to watch if you aren't one of the millions who've already seen it.
It's inspiring (and funny, and touching, and straightforward without being trite), and it reminds us all to keep our focus on what's important. My cynicism put itself on hold for those 11 minutes.